Cell Invasion in Collagen Scaffold Architectures Characterized by Percolation Theory

نویسندگان

  • Jennifer C Ashworth
  • Marco Mehr
  • Paul G Buxton
  • Serena M Best
  • Ruth E Cameron
چکیده

The relationship between biological scaffold interconnectivity and cell migration is an important but poorly understood factor in tissue regeneration. Here a scale-independent technique for characterization of collagen scaffold interconnectivity is presented, using a combination of X-ray microcomputed tomography and percolation theory. Confocal microscopy of connective tissue cells reveals this technique as highly relevant for determining the extent of cell invasion.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2015